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Research Training Program in the Genetic Architecture of Quantitative Traits

The National Institute of General Medical Sciences of the National Institutes of Health has awarded the Department of Genetics an Institutional Research Training Grant for pre-doctoral training in "The Genetic Architecture of Quantitative Traits."

 

 

   

Quantitative, or complex, traits are affected by multiple interacting genes, each of which have small effects and are sensitive to the environment.  Understanding the molecular nature of genetic variation for quantitative traits will have an enormous impact on medicine, livestock and crop breeding, and the study of evolution.  For over half a century North Carolina State University has been a leading center for research in quantitative genetics. To enable future scientists to advance our understanding of the genetic architecture of quantitative traits, we offer a research and  training program that integrates quantitative, population, molecular and  developmental genetics, statistics and molecular evolution.
 
Our program offers:

  • Stipend with tuition and health insurance
  • Travel allowance and research funds
  • State-of-the-art research facilities
  • Internationally recognized faculty with expertise in theoretical and experimental quantitative genetics
  • A stimulating academic environment near the University of North Carolina at Chapel Hill, Duke University and the Research Triangle Park
  • A beautiful and affordable location with a pleasant climate, between the beaches and the Appalachian mountains.
US citizens and permanent residents are eligible for Fellowships. 

The Department of Genetics is strongly committed to promoting diversity in the scientific community and encourages applications from individuals of historically under-represented minority groups.

For information and application materials, contact:

Director of Graduate Programs
Department of Genetics
North Carolina State University
Raleigh, NC 27695-7614
Telephone: 919-515-2292


Training Faculty

Jose Alonso
Analysis of the ethylene signal transduction pathway in Arabidopsis and development of tools for the functional characterization of Arabidopsis genome.
Email
http://www.cals.ncsu.edu/genetics/alonso/alonso.html

Robert Anholt
Molecular and quantitative genetics of odor recognition and olfactory behavior in Drosophila; molecular biology of vertebrate olfaction.
Email

http://www4.ncsu.edu/~anholt/

Philip Awadalla
Examination of how recombination, mating systems, and mutation co-evolve in model systems; approaches to measure the scale of recombination variation within genomes and across species.
Email
http://www.cals.ncsu.edu/genetics/awadalla/awadalla.html

William Atchley
Developmental quantitative genetics of complex morphological structures; long-term selection response for cell size and cell number in mice; molecular evolution of the basic helix-loop-helix family of transcriptional activators.
Email

http://www.cals.ncsu.edu/genetics/atchley/atchley.html
 
 
Patricia Estes
Developmental neurobiology, especially gene regulation during nervous system development and cellular and molecular response to hypoxia.
Email
http://www.cals.ncsu.edu/genetics/estes/estes.html

Robert Franks
Research on basic mechanisms of organ size and shape regulation in Arabidopsis thaliana and understanding the relationships between patterning cues and cellular proliferation.
Email
http://www.cals.ncsu.edu/genetics/franks/franks.html

Gregory Gibson
Molecular and quantitative variation in developmental pathways affecting wing shape, pupal heart rate and other quantitative traits in Drosophila; quantitative trait locus mapping; molecular genotype - phenotype associations at candidate genes.
Email

http://www.cals.ncsu.edu/genetics/gibson/gibson.html

Fred Gould
Ecological, genetic, and chemical aspects of plant/herbivore interactions, pest management and behavioral ecology of arthropods; strategies for developing genetically engineered crops.
Email
http://www.cals.ncsu.edu/entomology/gould/

Patrick Hurban
Elucidation of biological networks through integration of molecular profiling data; how network interactions give rise to growth and development, disease progression and toxicity.
Email

Todd Klaenhammer
Development of genetic systems in Gram-positive lactic acid bacteria and the use of genomic approaches to improve cultures for bioprocessing.
Email
http://ncsu.edu/foodscience/faculty/klaenhammer_todd.htm

Laura Mathies
Genetic analysis of early gonad development in C. elegans. Studies of early gonadal fate specification and translation of cell fates into gonad patterning.
Email
http://www.cals.ncsu.edu/genetics/mathies/mathies.html

James Mahaffey
Drosophila developmental genetics; identification, biochemical and functional analysis of genetic cofactors that act in conjunction with homeodomain class transcription factors.
Email
http://www.cals.ncsu.edu/genetics/mahaffey/mahaffey.html
 
Trudy Mackay
Molecular quantitative genetics of morphological, behavioral and life history traits in Drosophila; quantitative trait locus mapping; spontaneous mutation accumulation and P transposable element mutagenesis; molecular genotype - phenotype associations at candidate genes.
Email

http://www.cals.ncsu.edu/genetics/mackay/mackay.html

Ronald Sederoff
Molecular and quantitative genetics of lignin and cell wall biosynthesis in pine and maize; analysis of lignin mutations; pine genomics; quantitative trait locus mapping; microarray analysis of gene expression and DNA polymorphisms in pine.
Email
http://www.cfr.ncsu.edu/for/faculty/sederoff.html

Jeffrey Thorne
Statistical methods for analysis of DNA and protein sequence data; relationship between protein structure and protein evolution; estimation of evolutionary divergence times; sequence alignment; phylogenetic reconstruction.
Email
http://statgen.ncsu.edu/thorne/thorne.html

Shao-Bang Zeng
Quantitative genetic theory and statistical methodology for characterizing and analyzing quantitative genetic variation; statistical methods for mapping quantitative trait loci with extensions to multiple traits and epistatic interactions between loci.
Email
http://statgen.ncsu.edu/zeng/zeng.html


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Genetics Web display last changed 28 July 2007.

 

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