Paul Mozdziak

Educational Background:

• B.S. (1989) Cornell University
• M.S. (1991) University of Wisconsin
• Ph.D. (1994) University of Wisconsin

Research Interests:

The overall goal of my research program is to understand the cellular and molecular mechanisms governing skeletal muscle growth and muscle adaptation to changes in functional demands. My laboratory is especially interested in understanding the mechanisms governing myonuclear accretion, and in understanding the relationship between nutritional manipulations and myofiber growth. My laboratory has the expertise to employ immunocytochemistry, molecular biology, fluorescence microscopy, image analysis, tissue culture, and protein chemistry techniques to answer questions related to muscle growth.

Teaching Interests:

Animal Tissue Culture Techniques BIT 566/PO 566. Aseptic technique for vertebrate cell culture, media formulation, primary cell culture, long-term maintenance of cell lines, application of molecular techniques to in vitro situations. Half semester course. 2 Credits. Instructor.

Advising:

I advise non-thesis students in the Masters of Physiology Program, and undergraduate students in the Nutrition program.

I am a faculty member in the interdepartmental Graduate Programs in Biotechnology, Comparative Biomedical Sciences, Genomics, Nutrition, and Physiology Programs. Students who wish to pursue research based graduate degrees, under my direction, may complete programs in Biomedical Sciences, Genomics, Nutrition, Physiology, or Poultry Science.

Representative Publications:

• Mozdziak, P.E., S. Borwornpinyo, D.W. McCoy and J.N. Petitte. 2003. Development of transgenic chickens expressing bacterial beta- galactosidase. Dev Dyn 226:439-445.
• Giamario, C., J. N. Petitte, and P. E. Mozdziak. 2003. Hatchability of chicken embryos following somite manipulation . Biotechniques 34: 1128-1130.
• Mozdziak, P.E., J.J. Dibner and D.W. McCoy. 2003. Glyceraldehyde-3-phosphate dehydrogenase expression varies with age and nutrition status. Nutrition 19: 438-440.
• Mozdziak, P. E.., T. J. Walsh, and D. W. McCoy, 2002. The effect of early posthatch nutrition on satellite cell mitotic activity. Poult. Sci. (In Press).
• Mozdziak, P. E., J. J. Evans, and D. W. McCoy, 2002. Early posthatch starvation induces myonuclear apoptosis in chickens. J. Nutr. 132: 901-903
• Mozdziak, P. E. , P. M. Pulvermacher, and E. Schultz, 2001. Muscle regeneration during hindlimb unloading results in a reduction in muscle size following reloading. J. Appl. Physiol. 91: 183-190.
• Greaser, M. L., S. M. Wang, M. Berri, P. Mozdziak, and Y. Kumazawa, 2000. Sequence and mechanical implications of titin's PEVK region. Adv Exp Med Biol 481: 53-63.
• Mozdziak, P. E., P. M. Pulvermacher, E. Schultz, and K. Schell, 2000. Hoechst Fluorescence Intensity can be used to separate viable bromodeoxyuridine labeled cells from viable non-bromodeoxyuridine labeled cells. Cytometry 41: 89-95.
• Mozdziak, P. E., and E. Schultz, 2000. Retroviral labeling is an appropriate marker for dividing cells. Biotechnic & Histochemistry 75: 141-146.
• Mozdziak, P. E., P. M. Pulvermacher, and E. Schultz, 2000. Unloading of juvenile muscle results in a reduced muscle size nine weeks after reloading. J. Appl. Physiol. 88: 158-164.
• Dangott, B., E. Schultz, and P. E. Mozdziak, 2000. Dietary creatine monohydrate supplementation increases satellite cell mitotic activity during compensatory hypertrophy. Int. J. Sports Med. 21: 13-16.
• Mozdziak, P. E., E. Schultz, and R. G. Cassens, 1997. Myonuclear accretion is a major determinant of avian skeletal muscle growth. Am. J. Physiol. 272: C565-571.
• Mozdziak, P. E., E. Schultz, and R. G. Cassens, 1994. Satellite cell mitotic activity in posthatch turkey skeletal muscle growth. Poultry Sci. 73: 547-555.